玉研儀器自主研發(fā)腦立體定位儀十四年，適用于大鼠、小鼠等實(shí)驗(yàn)動(dòng)物，經(jīng)典十字操作臂實(shí)現(xiàn)精準(zhǔn)定位，精度可達(dá)10微米，特制螺紋精密螺桿，穩(wěn)固不晃動(dòng)實(shí)現(xiàn)對(duì)特定腦區(qū)的精確定位，是神經(jīng)環(huán)路研究、神經(jīng)系統(tǒng)性疾病、神經(jīng)藥理等領(lǐng)域內(nèi)的重要研究設(shè)備，廣泛面向全國各大科研院校,醫(yī)院,高新企業(yè),藥企,醫(yī)療機(jī)構(gòu)等科研單位。

小鼠腦立體定位儀是專門為小鼠準(zhǔn)備的定位儀，是為敲除基因小鼠實(shí)驗(yàn)和轉(zhuǎn)基因小鼠實(shí)驗(yàn)設(shè)計(jì)的。它是一款體積較小和比較經(jīng)濟(jì)的定位設(shè)備。

主要配置：包含3軸左手操作臂，小鼠嘴夾和齒桿，雙面耳桿，和一個(gè)角夾探頭支架。

小鼠專用型的腦立體定位儀采用了三大技術(shù)來牢固固定小鼠頭部：

1、輕質(zhì)的聚甲醛樹脂耳棒，前端逐漸變細(xì)；

2、特殊設(shè)計(jì)的下頜夾持器；

3、非植入性橡膠頭；

耳棒的高度可以獨(dú)立調(diào)節(jié)，垂直方向的刻度采用了激光雕刻技術(shù)，能夠非常新晰的讀出耳棒的高度。

1. 可以同時(shí)定位新生鼠和小型嚙齒類動(dòng)物

2. 底座尺寸：25cmx25cm

3. 兼容氣體

4. 耳棒和牙棒的高度調(diào)整適合10-75g小鼠

5. Delrin®材料的耳棒，更適合于小鼠實(shí)驗(yàn)操作

6. 三維操作臂可以精確定位

7. 支持雙操作臂工作模式

8. 可選數(shù)顯模式

9. 可選全自動(dòng)模式

10. 精確度標(biāo)準(zhǔn)型100um，數(shù)顯型10um

根據(jù)需求不同，有多種不同的型號(hào)可供選擇：單臂型，雙臂型，數(shù)顯型。

標(biāo)準(zhǔn)型小鼠腦定位儀  型號(hào)：SA-100

便攜式小鼠定位儀  型號(hào)：SA-103

數(shù)顯型小鼠腦定位儀  型號(hào)：SA-150

雙臂型小鼠腦定位儀   型號(hào)：SA-113

相關(guān)配件及可選配件：  

小動(dòng)物腦立體定位儀部分參考文獻(xiàn)：
1. Albéri, L., Lintas, A., Kretz, R., Schwaller, B., & Villa, A. E. (2013). The calcium-binding protein parvalbumin modulates the firing 1 properties of the reticular thalamic nucleus bursting neurons. Journal of neurophysiology, 109(11), 2827-2841.
2. Sonati, T., Reimann, R. R., Falsig, J., Baral, P. K., O’Connor, T., Hornemann, S., Aguzzi, A. (2013). The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature, 501(7465), 102-106.
3. Ali, I., O’Brien, P., Kumar, G., Zheng, T., Jones, N. C., Pinault, D., O’Brien, T. J. (2013). Enduring Effects of Early Life Stress on Firing Patterns of Hippocampal and Thalamocortical Neurons in Rats: Implications for Limbic Epilepsy. PLOS ONE, 8(6), e66962.
4. Bell, L. A., Bell, K. A., & McQuiston, A. R. (2013). Synaptic Muscarinic Response Types in Hippocampal CA1 Interneurons Depend on Different Levels of Presynaptic Activity and Different Muscarinic Receptor Subtypes. Neuropharmacology.
5. Bolzoni, F., B?czyk, M., & Jankowska, E. (2013). Subcortical effects of transcranial direct current stimulation (tDCS) in the rat. The Journal of Physiology.
6. Bolzoni, F., B?czyk, M., & Jankowska, E. (2013). Subcortical effects of transcranial direct current stimulation (tDCS) in the rat. The Journal of Physiology.
7. Babaei, P., Tehrani, B. S., & Alizadeh, A. (2013). Effect of BDNF and adipose derived stem cells transplantation on cognitive deficit in Alzheimer model of rats. Journal of Behavioral and Brain Science, 3, 156-161.
8. Gilmartin, M. R., Miyawaki, H., Helmstetter, F. J., & Diba, K. (2013). Prefrontal Activity Links Nonoverlapping Events in Memory. The Journal of Neuroscience, 33(26), 10910-10914.
9. Feng, L., Sametsky, E. A., Gusev, A. G., & Uteshev, V. V. (2012). Responsiveness to nicotine of neurons of the caudal nucleus of the solitary tract correlates with the neuronal projection target. Journal of Neurophysiology, 108(7), 1884-1894.
10. Clarner, T., Diederichs, F., Berger, K., Denecke, B., Gan, L., Van der Valk, P., Kipp, M. (2012). Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions. Glia, 60(10), 1468-1480.
11. Girardet, C., Bonnet, M. S., Jdir, R., Sadoud, M., Thirion, S., Tardivel, C., Troadec, J. D. (2011). Central inflammation and sickness-like behavior induced by the food contaminant deoxynivalenol: A PGE2-independent mechanism.Toxicological Sciences, 124(1), 179-191.
12. Hru?ka-Plocháň, M., Juhas, S., Juhasova, J., Galik, J., Miyanohara, A., Marsala, M., Motlik, J. (2010). A27 Expression of the human mutant huntingtin in minipig striatum induced formation of EM48+ inclusions in the neuronal nuclei, cytoplasm and processes. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A9-A9.
13. Brooks, S., Jones, L., & Dunnett, S. B. (2010). A29 Frontostriatal pathology in the (C57BL/6J) YAC128 mouse uncovered by the operant delayed alternation task. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A9-A10.
14. Yu, L., Metzger, S., Clemens, L. E., Ehrismann, J., Ott, T., Gu, X., Nguyen, H. P. (2010). A28 Accumulation and aggregation of human mutant huntingtin and neuron atrophy in BAC-HD transgenic rat. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A9-A9.
15. Baxa, M., Juhas, S., Pavlok, A., Vodicka, P., Juhasova, J., Hru?ka-Plocháň, M., Motlik, J. (2010). A26 Transgenic miniature pig as an animal model for Huntington’s disease. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A8-A9.

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